Single-Institution Experience with 696 Temporal Artery Biopsies for the Evaluation of Giant Cell Arteritis
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چکیده
منابع مشابه
Increased rho kinase activity in temporal artery biopsies from patients with giant cell arteritis.
OBJECTIVE Aberrant rho kinase (ROCK) activity is implicated in the pathogenesis of several vascular diseases and is associated with Th17 differentiation. Th17 immune response is recognized in the pathogenesis of GCA. The aim of this study was to assess ROCK activity in GCA. METHODS All patients who underwent temporal artery biopsy (TAB) at a tertiary care centre over 5 years were identified a...
متن کاملTemporal artery biopsy for giant cell arteritis: retrospective audit
OBJECTIVES Temporal artery biopsy (TAB) is performed in suspected cases of sight-threatening giant cell arteritis (GCA). We aimed to determine the feasibility of TAB in patients who are suspected of having GCA. DESIGN, SETTING AND PARTICIPANTS A retrospective audit of all patients undergoing TAB at a single teaching hospital between 2005 and 2011, identified from the histopathology database. ...
متن کاملAssociation between histological features in temporal artery biopsies and clinical features of patients with giant cell arteritis.
BACKGROUND In most cases of giant cell arteritis (GCA) the diagnosis is confirmed by temporal artery biopsy. Aside from the diagnostic purpose, histological parameters may serve as prognostic markers. OBJECTIVES To review positive temporal artery biopsies ofGCA in an attempt to correlate various histological parameters with clinical features, disease complications and outcome. METHODS Posit...
متن کاملElectron microscopy of giant-cell (temporal) arteritis.
Definitive histological studies of giant-cell (temporal) arteritis have been published by several workers (Harrison, 1948; Heptinstall, Porter, and Barkley, 1954; McCormick and Neuberger, 1958). The lesions are fairly uniform and have involved all layers of many different arteries and veins-large and small, intracranial as well as extracranial. The distinctive histological finding in this disea...
متن کاملNegative temporal artery biopsies: eventual diagnoses and features of patients with biopsy-negative giant cell arteritis compared to patients without arteritis.
OBJECTIVE Characterize patients with negative temporal artery biopsies in regard to their eventual diagnoses, and to find features that would differentiate biopsy-negative GCA from non-GCA patients. METHODS 58 patients with negative biopsies were included. Patients' data and final diagnoses were obtained from medical records. Biopsy-negative GCA was diagnosed when the American College of Rheu...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2016
ISSN: 1943-7722,0002-9173
DOI: 10.1093/ajcp/aqw161.047